Halfway as a result of his occupation, Cees Dekker reinvented himself. After several years of hardcore physics, he shifted his focus to ‘nanobiology’ with the turn of your millennium. A phrase he coined himself, for a make a difference of actuality.
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination perform.
Dynamics of initiation, termination and reinitiation of DNA translocation from the motor protein EcoR124I
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
That may be a dream of mine and we set to operate with a delightful dose of naivety. This is something which will most likely yield stunning brings about the for a longer time expression, but that doesn't make a difference. You shouldn't only want to operate on the queries of tomorrow, and also on the queries with the working day after tomorrow.’
Our analysis ranges from your biophysics of DNA to synthetic cells and past. Make sure you have a look beneath in the spectrum of our current projects.
‘At the beginning we checked out Organic devices which has a Actual physical see and acted on The idea of your tools we understood. It took a several years before we started out Performing extra on the large Organic difficulties. I then started to get in touch with it nanobiology, a time period that didn't exist at enough time.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
2003, demonstrated the very first biosensors made outside of a carbon nanotube; solved the framework and mechanism of DNA repair proteins; and discovery of a completely new system for fabricating stable-condition nanopores for DNA translocation
Dekker began his research on solitary carbon nanotubes in 1993 when he create a new line of investigate to review electrical transportation by way of single natural and organic molecules among nanoelectrodes. In 1996 a breakthrough was realized with carbon nanotubes. This was realized within a collaboration with the team of Nobel laureate Richard Smalley. STM and nanolithography methods ended up used to display that these nanotubes are quantum wires at the single-molecule amount, with exceptional Actual physical Qualities.
[fourteen] In 2005 Dekker became linked to Netherlands-broad conversations about Clever Design and style, a motion that he has given that Plainly distanced himself from. Dekker advocates that science and religion https://www.ceesdekker.net will not be in opposition but can be harmonized.
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained as being a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineties. Given that 2000, he moved to single-molecule biophysics and nanobiology. His present exploration focuses on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a living synthetic cell from lifeless molecules. Dekker is surely an elected member from the KNAW and fellow on the APS as well as the IOP.
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2013, managed shaping of Dwell bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations while in the handedness of histone tetrasomes